The World's First
Buccal Peptide
Patch
Tri-layer buccal patch delivering peptides directly to the bloodstream beyond pills and needles.
Inside the cheek, TD-IntelGel’s hydrogel enhances buccal absorption, allowing stabilized peptides to enter the bloodstream while bypassing the gut. A patented cold-mix process preserves peptide structure and potency.
The Challenge of Peptide Delivery
Why the world needs TD-IntelGel™
Route of Administration
Most therapeutic peptides require injection, as they degrade rapidly in oral delivery due to salivary enzymes, gastric exposure, and poor buccal membrane penetration caused by large molecular size.
Patient Compliance & Cost
Injectable therapies are invasive, expensive, and inconvenient, often requiring administration by a trained doctor or nurse. This leads to poor patient compliance and repeated clinic visits.
Stability Constraints
Peptides are extremely fragile biomolecules typically unstable at temperatures above 25 °C, making manufacturing, storage, and distribution highly challenging.
Route of Administration
Peptides typically range from 800 to 5,000 Daltons, while conventional buccal absorption is limited to molecules of approximately ≤400 Daltons, creating a significant biological delivery barrier.
TD-IntelGel™ redefines peptide delivery
The Solution
TD-IntelGelTM Patented Technology
coupled with Muco-Smart Seal®
TD-Intelegel™ Buccal dissolving Patch is the only globally patented technology that utilizes cold temperature manufacturing process that protects Lyophilized (freeze-dried) peptides in a stable matrix for maximum bioactivity. This world class technology offers a stabilized trans-diffusion peptide platform that bridges the gap between injection-level efficacy at oral convenience with Muco SmartSeal® Technology.
Inside the Science
After five years of research and advanced development, Neopep™ discovered TD-IntelGel™, a trans-diffusion hydrogel technology designed to enhance peptide stability and buccal absorption.
This proprietary system works together with Muco-SmartSeal® technology, which surrounds the patch edges to maintain prolonged contact with the buccal mucosa while preventing peptide loss into saliva. By protecting peptides from enzymatic degradation and wash-out into the stomach, the system enables efficient systemic delivery and enhanced bioavailability.
TD-IntelGel™ Coupled with Muco-SmartSeal®
Stability Constraints
Peptides are embedded in a stabilized hydrogel matrix for controlled trans-diffusion through the buccal membrane.
Moisture & Enzyme Protection
Protects peptides from moisture and enzymatic degradation to preserve bioactivity.
Enhanced Buccal Delivery
Improves absorption through buccal tissue while bypassing the gastrointestinal tract and first-pass liver metabolism.
SmartSeal® Protection
Muco-SmartSeal® prevents peptide leakage into saliva and wash-out into the stomach.
Improved Stability & Bioactivity
Maintains peptide stability, potency, and biological activity during delivery.
Non-Invasive Convenience
Eliminates needles, enabling painless and easy self-administration.
TD-Intelgel's Invitro Clinical Studies by
Permeapad (TM) proves
Tablets
1% efficacy
Capsules
2% efficacy
Oral Dissolving Strips
32% efficacy
TD-IntelGel™ Buccal Patch
81% efficacy
How to Use Neopep
1. Peel the pouch to open
2. Take the patch out
3. Place and gently press gel side against the inside of the cheek
4. Let dissolve for 3 minutes
How to Use Neopep
1. Peel the pouch to open
2. Take the patch out
3. Place and gently press gel side against the inside of the cheek
4. Let dissolve for 3 minutes
Our Product
Range
Advanced peptide formulations powered by TD-IntelGelTM technology for precise delivery, purity, and optimized absorption.
REBUILD
BPC-157 500 mcg + TB500 300 mcg
GLOW
GHKCu 3mg
STRENGTH
CJC 1295 + Ipamorelin 200mcg
ENERGY
NAD+ 100mg
IMMUNE
Thymosin alpha-1 500mcg
VITALITY
Glutathione 100mg
MITO
MOTSc 3mg + SS31 3mg
SLEEP
DSIP 100 mcg + Melatonin 1mg
FOCUS
Semax 200mcg + Dihexa 1mg
DESIRE
PT141 1mg + oxytocin 50mcg + aminophenyl pyrole 20mg
About NeopepTM
Advanced Peptide Delivery Innovation
NeopepTM developed TD-IntelGelTM, a patented tri-layer hydrogel buccal patch that delivers stabilized peptides through the cheek membrane. Combined with Muco-SmartSeal®, it protects peptides from saliva degradation and wash-out while improving bioavailability. Manufactured below 8°C, the process preserves peptide stability and activity.
NeopepTM is focused on advancing peptide delivery through innovative biotechnology. After years of research and development, the company introduced TD-IntelGelTM, a patented trans-diffusion hydrogel platform designed to enhance peptide stability and maximize buccal absorption. The technology works with Muco-SmartSeal®, enabling peptides to bypass the gastrointestinal tract and first-pass metabolism while protecting them from saliva and enzymatic degradation.
TD-IntelGelTM is engineered with a tri-layer hydrogel structure that stabilizes peptides and enables controlled trans-diffusion through the buccal membrane for efficient systemic delivery. The platform also uses a specialized cold-temperature manufacturing process below 8°C with gravitational mixing, preserving peptide integrity and biological activity while enabling convenient, non-invasive peptide delivery without injections.
Transforming Science Into
Real-World Wellness
Discover advanced peptide solutions designed to support recovery, vitality, and long-term health.